KIYAMA, Ryuichi : rechercher sur Z-Library

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1

Marked regression of liver metastasis by combined therapy of ultrasound-mediated NFkB-decoy transfer and transportal injection of paclitaxel, in mouse

Haruhito Azuma, Naruya Tomita, Takeshi Sakamoto, Satoshi Kiyama, Teruo Inamoto, Kiyoshi Takahara, Yatsugu Kotake, Naoki Segawa, Ryuichi Morishita, Shiro Takahara, Hana Hayasaki, Yoshinori Otsuki, Shig

Journal:

International Journal of Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 845 KB

english, 2008

2

Flexibly crown ether-capped β-cyclodextrin

Ikuo Fujii, Ryuichi Kiyama, Ken Kanematsu

Journal:

Bioorganic Chemistry

Année:

1989

Langue:

english

Fichier:

PDF, 225 KB

english, 1989

3

A platform for designing HIV integrase inhibitors. Part 2: A two-metal binding model as a potential mechanism of HIV integrase inhibitors

Takashi Kawasuji, Masahiro Fuji, Tomokazu Yoshinaga, Akihiko Sato, Tamio Fujiwara, Ryuichi Kiyama

Journal:

Bioorganic & Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 679 KB

english, 2006

4

A platform for designing HIV integrase inhibitors. Part 1: 2-Hydroxy-3-heteroaryl acrylic acid derivatives as novel HIV integrase inhibitor and modeling of hydrophilic and hydrophobic pharmacophores

Takashi Kawasuji, Tomokazu Yoshinaga, Akihiko Sato, Mitsuaki Yodo, Tamio Fujiwara, Ryuichi Kiyama

Journal:

Bioorganic & Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 595 KB

english, 2006

5

3-Hydroxy-1,5-dihydro-pyrrol-2-one derivatives as advanced inhibitors of HIV integrase

Takashi Kawasuji, Masahiro Fuji, Tomokazu Yoshinaga, Akihiko Sato, Tamio Fujiwara, Ryuichi Kiyama

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 188 KB

english, 2007

6

Synthesis and structure-activity relationships of dual histamine H2 and gastrin receptor antagonists with noncyclic gastrin receptor antagonistic moieties

Yasuyuki Kawanishi, Shoichi Ishihara, Ryuichi Kiyama, Sanji Hagishita, Tadahiko Tsushima, Michio Ishikawa, Yasunobu Ishihara

Journal:

Bioorganic & Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 665 KB

english, 1997

7

Synthesis and pharmacological properties of ureidomethylcarbamoylphenylketone derivatives. A new potent and subtype-selective nonpeptide CCK-B/gastrin receptor antagonist, S-0509

Sanji Hagishita, Yasushi Murakami, Kaoru Seno, Susumu Kamata, Nobuhiro Haga, Toshiro Konoike, Yasuhiko Kanda, Ryuichi Kiyama, Takeshi Shiota, Yasunobu Ishihara, Michio Ishikawa, Mayumi Shimamura, Koji

Journal:

Bioorganic & Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 1.80 MB

english, 1997

8

Alteration of glial cell line-derived neurotrophic factor family receptor alpha-2 mRNA expression and its co-expression with neuronal nitric oxide synthase in pelvic ganglia following unilateral cavernous nerve injury

Shin-ichi Hisasue, Ryuichi Kato, Ko Kobayashi, Takahiro Suetomi, Hiroshi Kiyama, Taiji Tsukamoto

Journal:

International Journal of Urology

Année:

2008

Langue:

english

Fichier:

PDF, 290 KB

english, 2008

9

Oxidative resolution with bakers' yeast for large-scale production of chiral 1,2-alkanediols

Tadashi Kometani, Yasufumi Morita, Hidefumi Yoshii, Yoshiharu Kiyama, Ryuichi Matsuno

Journal:

Journal of Fermentation and Bioengineering

Année:

1995

Langue:

english

Fichier:

PDF, 570 KB

english, 1995

10

Relationship between ethanol consumption rate and prochiral ketone reduction rate in bakers' yeast

Tadashi Kometani, Yasufumi Morita, Yoshiharu Kiyama, Hidefumi Yoshii, Ryuichi Matsuno

Journal:

Journal of Fermentation and Bioengineering

Année:

1995

Langue:

english

Fichier:

PDF, 270 KB

english, 1995

11

Kinetic studies on the interaction of nonlabeled antagonists with the angiotensin II receptor

Mariko Hara, Ryuichi Kiyama, Shigeyuki Nakajima, Tomoji Kawabata, Masaru Kawakami, Koichi Ohtani, Koji Itazaki, Toshio Fujishita, Masafumi Fujimoto

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 600 KB

english, 1995

12

Cavernous nerve injury elicits GAP-43 mRNA expression but not regeneration of injured pelvic ganglion neurons

Ryuichi Kato, Sumiko Kiryu-Seo, Yoshikazu Sato, Shinichi Hisasue, Taiji Tsukamoto, Hiroshi Kiyama

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 1.82 MB

english, 2003

13

Novel Angiotensin II Receptor Antagonists. Design, Synthesis, and in Vitro Evaluation of Dibenzo[a,d]cycloheptene and Dibenzo[b,f]oxepin Derivatives. Searching for Bioisosteres of Biphenyltetrazole Using a Three-Dimensional Search Technique

Kiyama, Ryuichi, Honma, Tsunetoshi, Hayashi, Kunio, Ogawa, Masayoshi, Hara, Mariko, Fujimoto, Masafumi, Fujishita, Toshio

Journal:

Journal of Medicinal Chemistry

Année:

1995

Langue:

english

Fichier:

PDF, 2.56 MB

english, 1995

14

Age-related alteration of neurturin receptor GFRa2 and nNOS in pelvic ganglia

Shin-ichi Hisasue, Ryuichi Kato, Takahiro Suetomi, Kazunori Kato, Kazuhiro Suzuki, Ko Kobayashi, Naoki Itoh, Hiroshi Kiyama, Taiji Tsukamoto

Journal:

Neurobiology of Aging

Année:

2006

Langue:

english

Fichier:

PDF, 408 KB

english, 2006

15

A disintegrin and metalloprotease with thrombospondin type1 motifs (ADAMTS-1) and IL-1 receptor type 1 mRNAs are simultaneously induced in nerve injured motor neurons

Masahiko Sasaki, Sumiko Seo-Kiryu, Ryuichi Kato, Shin-ichi Kita, Hiroshi Kiyama

Journal:

Molecular Brain Research

Année:

2001

Langue:

english

Fichier:

PDF, 825 KB

english, 2001

16

Carbamoyl Pyridone HIV-1 Integrase Inhibitors. 2. Bi- and Tricyclic Derivatives Result in Superior Antiviral and Pharmacokinetic Profiles

Kawasuji, Takashi, Johns, Brian A., Yoshida, Hiroshi, Weatherhead, Jason G., Akiyama, Toshiyuki, Taishi, Teruhiko, Taoda, Yoshiyuki, Mikamiyama-Iwata, Minako, Murai, Hitoshi, Kiyama, Ryuichi, Fuji, Ma

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 546 KB

english, 2013

17

Carbamoyl Pyridone HIV-1 Integrase Inhibitors. 1. Molecular Design and Establishment of an Advanced Two-Metal Binding Pharmacophore

Kawasuji, Takashi, Johns, Brian A., Yoshida, Hiroshi, Taishi, Teruhiko, Taoda, Yoshiyuki, Murai, Hitoshi, Kiyama, Ryuichi, Fuji, Masahiro, Yoshinaga, Tomokazu, Seki, Takahiro, Kobayashi, Masanori, Sat

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2012

18

Ligand−Protein DataBase: Linking Protein−Ligand Complex Structures to Binding Data

Roche, Olivier, Kiyama, Ryuichi, Brooks, Charles L.

Journal:

Journal of Medicinal Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 70 KB

english, 2001

19

Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Johns, Brian A., Kawasuji, Takashi, Weatherhead, Jason G., Taishi, Teruhiko, Temelkoff, David P., Yoshida, Hiroshi, Akiyama, Toshiyuki, Taoda, Yoshiyuki, Murai, Hitoshi, Kiyama, Ryuichi, Fuji, Masahir

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2013

20

Homology Modeling of Gelatinase Catalytic Domains and Docking Simulations of Novel Sulfonamide Inhibitors

Kiyama, Ryuichi, Tamura, Yoshinori, Watanabe, Fumihiko, Tsuzuki, Hiroshige, Ohtani, Mitsuaki, Yodo, Mitsuaki

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 302 KB

english, 1999

21

Synthesis and Evaluation of Novel Nonpeptide Angiotensin II Receptor Antagonists: Imidazo(4,5-c)pyridine Derivatives with an Aromatic Substituent.

KIYAMA, Ryuichi, FUJI, Masahiro, HARA, Mariko, FUJIMOTO, Masafumi, KAWABATA, Tomoji, NAKAMURA, Masuhisa, FUJISHITA, Toshio

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1995

Fichier:

PDF, 1.40 MB

1995

22

Synthesis and Evaluation of Novel Pyrazolo(1,5-a)pyrimidine Derivatives as Nonpeptide Angiotensin II Receptor Antagonists.

KIYAMA, Ryuichi, HAYASHI, Kunio, HARA, Mariko, FUJIMOTO, Masafumi, KAWABATA, Tomoji, KAWAKAMI, Masaru, NAKAJIMA, Shigeyuki, FUJISHITA, Toshio

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1995

Fichier:

PDF, 846 KB

1995

23

Damage-Induced Neuronal Endopeptidase (DINE/ECEL) Expression Is Regulated by Leukemia Inhibitory Factor and Deprivation of Nerve Growth Factor in Rat Sensory Ganglia after Nerve Injury

Kato, Ryuichi, Kiryu-Seo, Sumiko, Kiyama, Hiroshi

Journal:

Journal of Neuroscience

Année:

2002

Fichier:

PDF, 556 KB

2002